After testing positive for the BRCA-1 gene mutation, Danielle has a high risk of developing breast and ovarian cancers. Her choice of preventative surgery while her sister undergoes chemotherapy for breast cancer changes her life, and the hospital gives Danielle jars of her recently-removed ovaries, Fallopian tubes, uterus, and cervix. These jars of lady parts become Danielle's confidants and advisors, dictating her life as she navigates how she and her family aren't just cancer survivors, but survivors of each other. Lady Parts is a dramedy-fantasy that tackles the complicated ridiculousness that cancer paints over everything. Sometimes simple questions don't have simple answers.
Devin Sidell, who will be playing Danielle, is BRCA-1 positive and underwent a preventative oophorectomy/hysterectomy in November 2016 while her older sister was undergoing chemotherapy for Triple-Negative, Stage 2B breast cancer. Sidell’s mother survived Stage 4 ovarian cancer in 1994, but her mother’s sister passed away from the same cancer in 1996. In December 2017, Sidell opted to undergo a preventative double-mastectomy. However, she has not undergone reconstructive surgery specifically to play the role of Danielle realistically. She will openly exhibit her scars and expanders so that the audience can truly get a feeling for what a difficult decision this is and how the aftermath honestly looks.